正常豚鼠清醒状态心电图分析

Non-narcotic Normal ECG Analysis of Guinea Pig

目的:取148例正常白化豚鼠雌雄各半,测定清醒状态下的心电图并对其进行分析。方法:使豚鼠保持自然的俯卧位,把微型针状电极植入豚鼠的右前肢和左后肢,用多导生理记录仪记录豚鼠肢体Ⅱ导联心电图。采用ADinstruments心电图分析软件对其进行分析。结果:①148例豚鼠均为窦性心律。②正常豚鼠心电图的波形与人极为相似,有明显的T波和S-T段。③148例豚鼠的平均心率为(264.57±27.70)次/min,P波持续时间平均(0.0272±0.0037)s,P-R间期平均(0.0629±0.0055)s,平均QRS间期(0.0315±0.0034)s,平均Q-T间期(0.1284±0.0160)s,校正Q-T间期平均(0.2678±0.0251)s,P波波幅平均(0.1075±0.0553)mV。④各指标雌雄之间无显著性差异。

Objective：To determine and analyze the ECG of 148 normal albino guinea pigs,half male and half female,which were under the conscious state. Methods：Keep the guinea pigs at the naturally prone position,insert the micro acicular electrodes to the right forelimb and left hindlimb of the guinea pig,the Ⅱ lead ECG of the guinea pigs was recorded by the polygraph. AD instruments,ECG analysis software,were used to analyze the records. Results：All 148 guinea pigs were measured with the sinus rhythm. ② The ECG waveforms of the normal guinea pigs,which have the evidently T wave and S-T wave,were similar as the human＇s. ③ The average heart rate of the 148 guinea pigs was（264.57±27.70）times per min,the average duration of the P wave was（0.0272±0.0037）s,the average P-R interval was（0.0629±0.0055）s, the average QRS interval was（0.0315±0.0034）s,the average Q-T interval was（0.1284±0.0160）s,the calibration of the Q-T interval wa（s0.2678±0.0251）s,the average P wave amplitude wa（s0.1075±0.0553） mV. ④ There was no significant difference between the indicate of the male and female guinea pigs.