43例早发型重度子痫前期期待治疗的临床分析

Clinical analysis on expectant management in 43 cases of early onset severe preeclampsia.

目的探讨早发型重度子痫前期期待治疗对母婴预后的影响。方法回顾分析43例早发型重度子痫前期患者,根据其发病孕周分为3组:A组孕周<28周,B组孕周28～31+6周,C组孕周32～34周,比较3组患者期待治疗的平均时间,并发症和围生儿结局。结果早发型重度子痫前期3组患者并发症发生率差异无统计学意义(P>0.05),新生儿病死率和围生儿病死率随着发病孕周的延长及治疗时间的延长而显著降低(P<0.05)。结论早发型重度子痫前期严重影响母婴预后,适当期限内保守治疗有助于改善母儿结局。

Objective To investigate the effects of expectant management on the maternal and/or infant outcomes in pregnant women with early onset severe preeclampsia.Methods A retrospective study was carried out on 43 patients with early onset severe preeclampsia from Jul 2004 to Dec2008.They were divided into three groups according to hospitalizd week of gestation：group A（〈28wks）,groupB（28～32wks）,and group C（32～34wks）.Results There was no significant difference about the maternal complication rates in early onset severe preeclampsia among the gestational week groups（p〉0.05）.The perinatal and neonatal mortality rates declined along with the prolongation of onset week and time of treatment（P〈0.05）.Conclusion The early onset severe preeclampsia badly influences the maternal and neonatal outcome.The expectant treatment contributes to the improvement of maternal and perinatal outcomes.