7Minoshima B, Giordani S, Berent K,et al. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer' s disease [J]. Ann Neurol, 1997,42 (1):85-94.
8Silverrnan DH, Small GW, Chang CY, et al. Positron emission tomography in evaluation of dementia: regional brain metabolism and long-term outeome[J]. JAMA, 2001, 286 (17): 2120- 2127.
9Price JL, Morris JC. Tangles and plaques in nondemented aging and "preclinical"Alzheimer's disease[J]. Ann Neurol, 1999,45 (3) :358-368.
10Alavijeh MS, Chishty M, Qaiser MZ, et al. Drug metabolism and pharmacokinetics, the blood-brain barrier, and central nervous system drug discovery[J]. NeuroRx, 2005,2 (4) : 554-571.