对1,3-丙二醇发酵液用金属纳滤膜过滤的研究

Study on Filtration of 1,3-propanediol Broth by Metal Nanofiltration Membrane

考察了l,3-丙二醇发酵液金属膜过滤在不同条件下的通量、收率及蛋白含量的变化。在此基础上,初步探讨了膜的过滤机理,确定了金属膜过滤的工艺参数。结果表明,100 nm膜适用于过滤1,3-丙二醇发酵液,按料液体积20%从开始过滤2h后就持续加入去离子水,在4.2/3.6 MPa压力下,60℃,pH值为7的条件下,5h内完成过滤,并且收率达到87%以上,运行时间短而且对后续工艺压力最小。

The change of flux,yield and protein content of Filtration of 1,3-propandio broth by metal membrane at different conditions.Base on it,the filter mechanism of membrane is studied,the parameters of filtration by metal membrane are determined.The result shows,100 nm membrane is suitable for filtration of 1,3-propanediol broth,deionized water is sustainale added with 20% after 2 hours from start filtering,at 4.2/3.6 MPa pressure,60 ℃,pH value is 7,5 h to complete filtration,the yield is 87% or more,the running time is short and the pressure is minimum for the following process.