西沙比利治疗新生儿窒息后喂养不耐受的疗效观察

Observation on Efficacy of Oral Cisapride in Treating Feeding Intolerance in Suffocated Neonates

目的:观察西沙比利口服治疗新生儿窒息后喂养不耐受的疗效。方法:86例窒息后喂养不耐受新生儿通过随机数表法随机分为治疗组44例,对照组42例,对照组按常规予进食后半卧位,治疗组在此基础上加用西沙比利0.3mg/(kg.次),1次/8h口服,观察两组患儿的疗效。结果:治疗组有效率(93.18%)优于对照组(73.81%),两组比较差异有统计学意义(P<0.05)。结论:西沙比利可加速胃排空,促进肠道蠕动,尽快恢复胃肠功能。西沙比利口服治疗新生儿窒息后喂养不耐受疗效显著。

Objective：Observation on efficacy of oral cisapride in treatment of feeding intolerance in suffocated neonates.Methods：Eighty-six cases of suffocated neonates with feeding intolerance were randomly divided into two groups,and the control group took semi-recumbent position after given conventional feeding while the treatment group was given oral cisapride（0.3 mg/kg,orally every 8 hours）in addition.And then the efficacy of the two groups was observed.Results：The treatment group was more effective than the control group and there was a significant difference between the two groups（93.18% vs 73.81%,P〈0.05）.Conclusions：Cisapride can accelerate gastric emptying,promote intestinal peristalsis and early resumption of gastrointestinal function.Efficacy of oral cisapride in treatment of feeding intolerance in suffocated neonates is significant.