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胃癌组织中碳酸酐酶Ⅸ和VEGF的表达及其临床意义 被引量：3

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摘要 目的探讨碳酸酐酶Ⅸ(CAⅨ)和血管内皮生长因子(VEGF)在胃癌组织中的表达及其临床意义。方法应用免疫组化方法检测56例胃癌组织及癌旁正常组织中CAⅨ和VEGF的表达。结果胃癌组织中CAⅨ和VEGF的阳性表达率分别为69.6%(39/56)和73.2%(41/56),在癌旁正常组织无表达,CAⅨ和VEGF的阳性表达率与肿瘤大小、分化程度、TNM分期及淋巴结转移有关,随分化程度的降低及TNM分期的进展逐渐增高(<0.05),随肿瘤直径的增大及淋巴结转移而增加(<0.01);CAⅨ和VEGF的表达相关性不强。结论CAⅨ和VEGF参与胃癌的发生、发展和浸袭转移,但两者可能无协同作用。
作者 徐晓武 杨小敏 朱少俊 冯国飞
机构地区 温州医学院附属第二医院 浙江省温州市第三人民医院
出处 《现代实用医学》 2009年第11期1206-1207,F0003,共3页 Modern Practical Medicine
关键词 胃肿瘤 碳酸酐酶Ⅸ 血管内皮生长因子 免疫组化
分类号 R735.2 [医药卫生—肿瘤]
  • 相关文献

参考文献13

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共引文献2

同被引文献31

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现代实用医学
2009年 第11期

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