摘要
应用德诺三联用药(低剂量三联疗法)治疗幽门螺杆菌(HP)阳性慢性胃炎患者。41例HP阳性病人3种药物(DeNol240mg,甲硝唑04,阿莫西林05)于早晚餐后服用,共服14d,HP根除率为8770%,慢性炎好转率为6098%,活动性炎好转及消失率分别为6585%,1707%;慢性胃炎伴肠上皮化生26例,肠化生减轻和消失11例,占4231%。
To investigate the
relationship between nitric oxide and membrane lipid peroxidation in viral myocarditis,we used
the murine model of Coxsakievirus B 3 induced myocarditis (four week old Balb/c male mice
were inoculated intraperitoneally with 5×10 3 PFU Coxsakievirus B 3 in 0 3 ml fetal bovine
serum),then divided them to two groups randomly 0 05 mg L arginine in 1 ml drinking water
was given to each mouse in the first group p o twice a day The second group was only given
drinking water The result showed the level of nitric oxide in the first group was significantly
higer than that in the second group(53 17±8 80,30 80±8 60, P <0 01) So was the level of
MDA(12 30±1 80,9 90±1 60, P <0 01),but the SOD activity in the first group was much
lower than that in the second group(64 30±12 80,79 80±14 20, P <0 01) Histologically,the
degree of myocardial damage in the first group was more serious than that in the second group
Therefore,nitric oxide may aggravate membrane lipid peroxidation and exacerbate myocardial
damage in viral myocarditis
关键词
胃炎
药物疗法
幽门螺杆菌
德诺
MeSH myocarditis,viral
nitric oxide
membrane lipid
peroxidation