2010年黑色素瘤治疗新进展

Development of Melanoma Therapy in 2010

长期以来,黑色素瘤的治疗一直难有实质性的突破。2010年ASCO年会公布了多项黑色素瘤的研究,免疫靶向药物ipilimumab能延长Ⅳ期黑色素瘤患者的生存,这是近30年来晚期黑色素瘤治疗的重大进步。个体化靶向治疗初显疗效,新技术用于肝转移的治疗更是带来了曙光。阳性结果让人振奋的同时,阴性的研究结果也带给人更多的思考。

The treatment for melanoma has lacked of substantial progress for a long period of time.Several studies about melanoma are reported at ASCO 2010 Annual Meeting,including that immunotarget drug ipilimumab can prolong the survival of melanoma patients in stage IV,that is an important progress in advanced melanoma therapy during the past 30 years.Individual target therapy showes preliminary effect,and new technique sheds a great light on the treatment of patient with liver metastases.While positive outcomes are exciting,negative outcomes also bring revelation to melanoma therapy.