枯草杆菌二联活菌肠溶胶囊联用5-氨基水杨酸治疗溃疡性结肠炎64例被引量：10

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摘要目的评价益生菌在轻中度溃疡性结肠炎的活动期与完全缓解期治疗的作用。方法选择轻中度溃疡性结肠炎患者,观察组予枯草杆菌二联活菌肠溶胶囊(美常安)联用5-氨基水杨酸(美迪莎),对照组单用5-氨基水杨酸,8周后复查肠镜观察疗效,在完全缓解患者维持治疗中,观察组单用枯草杆菌二联活菌肠溶胶囊,对照组单用5-氨基水杨酸。结果在溃疡性结肠炎活动期,5-氨基水杨酸联用枯草杆菌二联活菌肠溶胶囊可取得更高的完全缓解率,在维持治疗中,单用枯草杆菌二联活菌肠溶胶囊的效果与5-氨基水杨酸差异无统计学意义,且无不良反应。结论溃疡性结肠炎患者以益生菌联用5-氨基水杨酸在活动期治疗治疗效果优于单用5-氨基水杨酸,完全缓解后维持治疗中可取得与5-氨基水杨酸相同的效果。

作者秦荣朱淑军王光恺

机构地区广东省东莞市太平人民医院消化科

出处《广东医学》 CAS CSCD 北大核心 2010年第13期1739-1740,共2页 Guangdong Medical Journal

关键词溃疡性结肠炎 5-氨基水杨酸益生菌枯草杆菌二联活菌肠溶胶囊

分类号 R574.62 [医药卫生—消化系统]

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