SiO_2-SO_3H异相催化一步合成9-芳基-3,4,5,6,7,9-六氢-1H-氧杂蒽-1,8(2H)-二酮

SiO_2-SO_3H mediated highly efficient one-pot synthesis of 9-aryl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione

以硅胶磺酸(SiO2-SO3H)为催化剂,4-芳硫基芳醛和1,3-环己二酮为原料,于乙醇中合成了标题化合物。该方法具有处理方便、反应时间短、产率高、催化剂价廉易得、可回收重复使用等优点。

A highly efficient one-pot synthesis of 1,8-dioxo-octahydroxanthene derivatives catalyzed by sulfonic acid covalently anchored onto the surface of silica gel in EtOH was reported.The silica sulfuric acid catalyst（SiO2-SO3H,SSA） was completely heterogeneous and could be recycled for eight consecutive runs without significant loss of activity.This method provides several advantages such as simple work-up,environmental friendliness and shorter reaction time along with high yields.