实验性胃粘膜癌前病变大鼠舌与胃粘膜象观察

Observation on Manifestations of Tongue .and Gastric Musosa in Rats with Experimental Precancerous Lesion of Gastric Mucosa

为了观察实验性胃粘膜癌前病变大鼠的舌与胃粘膜相关变化,以健康雄性Wistar大鼠造成胃粘膜癌前病变模型,对照观察了健康与造模组大鼠的舌、舌面pH值、舌苔脱落细胞、舌组织学及相应的胃粘膜,胃液pH值,粘膜组织学改变。结果示:胃粘膜癌前病变大鼠的舌苔以少苔或无苔,舌质以紫暗或有瘀斑为主,舌与胃液pH值升高,与胃气亏虚、瘀血阻络证型吻合。

Healthy male Wistar rats were prepared as model of precancerous lesion of gastric mucosa. The tongue, pH of tongue surface, dropped cells from tongue fur, histology of tongue. and corresponding gastric mucosa, pH of gastric juice, mucosal histological changes in both groups were observed. Results revealed that, in the rats with precancerous lesion, the tongues were bare or only with little fur, dark purplish tongue with petechia. pH of both tongue and gastric juice were high, which were both coincided with the syndrome type of asthenic gastric - qi and blockage of collaterals by stagnant blood.