24小时尿钠测定指导患者低钠饮食效果观察

EFFECT OF DETERMINATION OF 24-HOUR URINARY SODIUM AS A DIRECTION ON LOW SODIUM DIET

目的评价根据进行24小时尿钠检测指导患者低盐饮食的临床效果。方法将80例慢性肾脏病患者随机分为两组,A组,患者每4周行24小时尿钠排泌定量检测,并据此计算出患者钠摄入量,用以监测及指导患者控制饮食中的钠摄入量,B组(对照组),对患者进行低钠饮食宣教,每4周行24小时尿钠排泌测定,以评估患者实际钠摄入量。两组病人追踪随访6个月。结果干预前两组患者钠摄入量无显著差异,通过不同的方法进行低盐饮食干预后,通过测定尿钠排泌计算出患者钠摄入量的患者,从第16周起,A组患者的钠摄入量比干预前以及对照组的钠摄入量均显著减少,差异具有统计学差异。结论使用24小时尿钠测定的方法来监测及指导患者低钠饮食,比常规的低盐饮食宣教能更好地促使患者达到低盐饮食的效果。

Objective This study was designed to investigate the effect of using determination of 24 - hour urinary sodium as a guide on Low Sodium Diet. Methods 80 patients with chronic kidney disease were randomly divided into two groups, Group A and B. According to patient＇ s 24 - hour urinary sodium which was measured every four weeks, the sodium intake were calculated in group A. The result was used to direct and adjust the patient＇ s sodium intake diet individually. In group B, we recommend low sodium diet to patients by publicity and education. To assess the actual sodium intake in patient＇ s 24 - hour urinary sodium were also measured in group B every four weeks. Two groups of patients were followed up for 6 months. Results There was no significant difference in the sodium intake between two groups before intervention. From Week 16 the sodium intake in A group was lower than in the B group（p 〈0. 05）. In comparison with the baseline values, there was a significant reduction in sodium intake in the group A （p 〈 0.05 ）. Conclusion Using determination of 24 - hour urinary sodium as a direction on low sodium diet is more effective than conventional education in implementation of low sodium diet in patients.