摘要
肺动脉高压是一种威胁儿童生命的严重疾病。近10年来有关肺动脉高压的治疗取得了很大进展。目前有3类药物(前列环素类药物、内皮素受体拮抗剂及5型磷酸二酯酶抑制剂)在肺动脉高压患者治疗研究中取得很大进步,但多中心的随机对照研究尚待加强。房间隔切开术和心肺移植对于内科治疗无效的肺动脉高压患儿有一定疗效。
Pulmonary hypertension (PH) is a life-threatening disease in children. In the last decade the treatment of PH has improved. Three classes of drugs (prostanoids, endothelin receptor antagonists, and phosphodiesterase inhibitors) have been extensively studied for treatment of PH. However, there are no data from muhicenter randomized clinical trial. Atrial septostomy and lung or combined heart and lung transplantation is considered as the last chance for non-responders to medical treatment.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2010年第7期607-610,共4页
Journal of Clinical Pediatrics
关键词
肺动脉高压
儿童
治疗
pulmonary hypertension
children
treatment