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肺动脉高压的治疗现状与进展 被引量：22

Progress on treatment of pulmonary hypertension in children
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摘要 肺动脉高压是一种威胁儿童生命的严重疾病。近10年来有关肺动脉高压的治疗取得了很大进展。目前有3类药物(前列环素类药物、内皮素受体拮抗剂及5型磷酸二酯酶抑制剂)在肺动脉高压患者治疗研究中取得很大进步,但多中心的随机对照研究尚待加强。房间隔切开术和心肺移植对于内科治疗无效的肺动脉高压患儿有一定疗效。 Pulmonary hypertension （PH） is a life-threatening disease in children. In the last decade the treatment of PH has improved. Three classes of drugs （prostanoids, endothelin receptor antagonists, and phosphodiesterase inhibitors） have been extensively studied for treatment of PH. However, there are no data from muhicenter randomized clinical trial. Atrial septostomy and lung or combined heart and lung transplantation is considered as the last chance for non-responders to medical treatment.
作者 张清友 杜军保
机构地区 北京大学第一医院儿科
出处 《临床儿科杂志》 CAS CSCD 北大核心 2010年第7期607-610,共4页 Journal of Clinical Pediatrics
关键词 肺动脉高压 儿童 治疗 pulmonary hypertension children treatment
分类号 R543.2 [医药卫生—心血管疾病]
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参考文献18

  • 1Badesch DB,Champion HC,Scanchez MA,et al.Diagnosis and assessment of pulmonary arterial hypertension[J].J Am Coll Cardiol,2009,54(1 Suppl):55-65.
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二级参考文献12

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共引文献14

同被引文献271

引证文献22

二级引证文献90

临床儿科杂志
2010年 第7期

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