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紫癜性肾炎发病机制与血清IgA1关系的研究 被引量:4

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摘要 紫癜性肾炎(HenEch-SchEnlein purpura nephritis,HSPN)是继发于过敏性紫殿(HSP)的肾小球肾炎,也是较为常见的继发性肾小球疾病。其病因和发病机制可能与感染、药物、食物及免疫异常、遗传机制等有关,主要涉及免疫学异常,其中以体液免疫异常为主。随着近年来国际对于继发性肾脏疾病的发病机制及疾病进展相关研究的不断深入,紫癜性肾炎的发病机制较前也有了更加全面的认识,对于其与人体内免疫复合物含量水平的相关性研究较前也有了更多的实验证据,但国内对此方面的研究较少,报道尚不多见。从免疫方面具体阐述紫癜性肾炎与免疫复合物,主要是IgA1的关系及其意义。
机构地区 中国医科大学
出处 《亚太传统医药》 2010年第7期167-168,共2页 Asia-Pacific Traditional Medicine
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