1988～1992年中国联体双胎流行病学调查

Epidemiological Survey of Conjoined Twins in China

为了解联体双胎在我国的发生率及流行病学特征，作者在１９８８～１９９２年期间，采用以医院为单位的整群抽样方法，对全国５００多所医院孕２８周至产后７天的围产儿进行了监测。结果：共监测出联体双胎１０６例，５年围产儿数３２４６４０８，全国平均畸形率为０．３／万。河南、安徽省最高，为０．８／万（Ｐ＜０．０５）；北京市和吉林省最低，为０．１／万（Ｐ＜０．０１）；城镇与乡村比较无显著性差异；女性胎儿的联体双胎畸形率比男性胎儿高２倍多；联体双胎死亡率为９１５‰；产前确诊率３１．１３％。上述结果表明，联体双胎是一种死亡率很高的畸形，在我国其发生率与西方国家相近，更多见于女性，我国的联体双胎产前诊断率低，尚有待提高。

A descriptive study was conducted to investigate the incidence and epidemiological characteristics of conjoined twins in China. From 1988 to 1992, data were collected from more than 500 hospital based units involved in a monitoring program and were analyzed by the National Center for Birth Defects Monitoring. The monitored subjects were the hospitalized births from 28 weeks gestation to a period within 7 days after delivery. 106 conjoined twins were found in 3 246 408 births with an incidence rate of 0.3/10 000.The highest rate was 0.8/10 000 in He'nan Province and Anhui Province( P <0 05), and the lowest 0.1/10 000 in Beijing and Jilin Province ( P <0 01). Conjoined twins were more common in females; the ratio of female to male was 2 to 1. No difference was observed between the urban and rural areas. The prenatal mortality was as high as 915‰.Only 31.13% conjoined twins were diagnosed prenatally. The results indicate that the incidence of conjoined twins in China is not different from that in other countries, but the work of prenatal diagnosis in China should be improved.