住院患儿急性下呼吸道感染病毒学调查

Investment of Viral Pathogens in Children Hospitalized with Acute Lower Respiratory Infection

目的了解住院患儿急性下呼吸道感染(acute lower respiratory infection,ALRI)的病毒感染状况,为临床儿童ALRI提供病毒病原学诊断依据。方法选择2008年10月至2009年5月在九江市妇幼保健院呼吸内科住院的ALRI患儿179例,取其入院当天静脉血,进行呼吸道病毒Ig M检测,包括呼吸道合胞病毒(RSV)、腺病毒(ADV)、流感病毒(IV)、副流感病毒(PIV),并对检测标本阳性的病例进行统计分析。结果 179例送检标本,阳性39例,占21.7%(39/179)。在39例阳性标本中,RSV34例、占87.2%,ADV1例、占2.6%,IV2例、占5.1%,PIV2例、占5.1%。RSV感染的发病高峰在1、12月份,RSV感染多见于3岁以下儿童,男、女发病比例为2.09∶1。结论本院2008年10月至2009年5月住院患儿中,引起ALRI的病毒病原体以RSV为主,IV和PIV次之。

Objective To investigate viral etiology of acute lower respiratory infection （ALRI） in children hospitalized and provide viral etiology evidence of diagnosis of ALRI. Methods The four respiratory viruses IgM including respiratory syncitail （RSV）, adenovirus （ADV）, influenza （IV） and parainfluenza （PIV） were detected in venous blood on the 1st hospital day for the chil- dren with ALRI in respiratory department of the maternal and children hospital of Jiujiang from October 2008 to May 2009. Statistical analysis was done in all positive specimens. Results In to- tally 179 samples, 21. 7%（39/179） was shown to be viral positive. 34（87. 2%） samples were RSV,I（2.6~）samples were ADV,2（5.1%）samples were 1V,2（5.1%）samples were PIV. The peak season of RSV infection was between January and December. Most children with RSV infec- tion were yonger than 3 years old. The ratio of male to female was 2.09 ： 1. Conclusion RSV is the most common viral pathogen in children hospitalized with acute lower respiratory infection in our hospital, the second one was IV and PIV.