银杏达莫注射液治疗血管性痴呆患者的疗效观察

GINKGO BILOBA EXTRACT AND DIPYRIDAMOLE INJECTION IN PATIENTS WITH VASCULAR DEMENTIA AND CLINICAL OBSERVATION

目的探讨银杏达莫在治疗血管性痴呆患者中的疗效。方法选择80例老年血管性痴呆患者随机分成治疗组和对照组。治疗组应用银杏达莫联合吡拉西坦治疗,对照组应用丹参联合吡拉西坦治疗,均1个月。治疗前后分别采用简易精神状态检查量表(MMSE)和日常生活能力量表(ADL)进行评价。结果治疗组治疗后MMSE评分高于对照组(P<0.05);治疗组治疗后ADL评分明显低于对照组(P<0.05)。结论银杏达莫注射液能明显改善血管性痴呆患者的认知功能及提高日常生活能力。

Objective To observe the curative effects of Ginkgo dipyridolum injection in the treatment of vascular dementia.Methods 80 patients with vascular dementia were randomly divided into two groups.40 patients in the Ginkgo dipyridolum group were treated with Ginkgo dipyridolum injection along with piracetam intravenously.40 patients in the control group were treated with Salvia injection along with piracetam intravenously,once a day.All treatments lasted one month.Mini-mental state examination （MMSE） and activities of daily living （ADL） were used to evaluate the curative effects before and after treatments.Results After treatments,the MMSE score was higher than that in the control group （P0.05）,but the ADL score was significantly lower than that in the control group （P0.05））.Conclusion Ginkgo dipyridolum injection can improve cognitive functions and the activities of daily living of patients with vascular dementia.