中药加植骨支撑术治疗早期股骨头坏死的临床研究

THE CLINICAL STUDY OF COMBINED TREATMENT OF BONE GRAFT AND THE TRADITIONAL CHINESE MEDICINE ON EARLY-STAGE OSTEONECROSIS OF THE FEMORAL HEAD

目的探讨活血补肾中药加植骨支撑术治疗早期股骨头坏死的疗效。方法对44例50髋采用口服活血补肾中药加植骨支撑术治疗早期股骨头坏死患者和46例50髋单纯口服活血补肾中药治疗患者的临床资料进行回顾性研究。治疗18个月后,根据Harris髋关节评分系统进行治疗前后的关节功能评价,根据ARCO分期系统进行影像学评价。结果中药加植骨支撑术治疗组影像学有进展者7髋,进展率为14%;中药治疗组有进展者15髋,进展率为30%;Harris评分,中药加植骨支撑术治疗组有进展者6髋,进展率为12%;中药治疗组影像学有进展者14髋,进展率为28%;两组进展率的比较有显著性差异(P<0.05)。结论活血补肾中药配合植骨支撑术治疗早期股骨头坏死疗效满意,能促进坏死修复,延缓影像学进展。

Objective To explore the curative effect about the combined treatment of bone gragt and the traditional Chinese medicine（TCM）Bushenhuoxuefang on early- stage osteonecrosis of the femoral head（ONFH）.Methods A retrospestive study was carried out.It included 44 patients with 50 hip-jiont early-stage ONFH treated by combination of bone graft and TCM,and 46 patients with 50 hip-jiont early-stage ONFH treated by TCM,90 patients with 100 hip-jiont received follow up surveys for average 18 months.The curative effects were evaluated according to Harris Scoring system as well as the radiography grading system of ARCO.Results Assessed by ARCO,in 44 patients group,7 hip-joints had improved with an improvement rate of 14% and in 46 patients group,15 hip-joints had improved with all improvement rate of 30%.It had significant difference between the two groups（P0.05）.Assessed by Harris Hip Score,6 hip-joints in 44 patients group improved with an improvement rate of 12% and 14 hip-joints in 46 patients group inproved with an improvement rate of 28%.It also had significant difference between the two groups（P0.05）.Conclusion Combined treatment of bone graft and TCM on early-stage ONFH proves to have good curative effects in the short-term treatments.It can promote the restoration and prevent the development of ONFH.