家庭无创辅助通气对慢性阻塞性肺疾病患者肺功能的影响

Effect of non-invasive assisted ventilation at home on the lung function in patients with chronic obstructive pulmonary disease

目的探讨稳定期慢性阻塞性肺疾病(COPD)患者家庭无创辅助通气治疗对患者肺功能及血气分析的影响。方法研究纳入稳定期COPD患者29例,其中治疗组16人,对照组13人。治疗组采用间断家庭无创辅助通气治疗,每日呼吸机使用时间>6 h。结果与对照组相比,治疗组患者6个月后的肺功能及血气分析指标均有明显改善。结论家庭无创辅助通气治疗能够改善稳定期COPD患者的肺功能及血气分析指标,改善日常症状。

Objective To investigate the effect of non-invasive assisted ventilation（NIAV） at home on the lung function and blood gas analysis in patients with chronic obstructive pulmonary disease（COPD） in the stable phase.Methods 29 COPD patients in the stable phase were spontaneously divided into the treatment group（n=16） and the control group（n=13）.All the patients in the treatment group underwent intermittent NIAV therapy at home,with the duration of their daily use of the ventilator over 6 hours.Result In contrast with the control group,the lung function and blood gas analysis of the treatment group were evidently improved at the end of 6 months of therapy.Conclusion The treatment of home NIAV can improve the parameters of lung function and blood gas analysis as well as the daily symptoms in COPD patients in the stable phase.