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相转移催化剂在香豆素衍生物中的应用 被引量:2

Application of Phase Transfer Catalyst in the Coumarin Derivatives
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摘要 为加快合成香豆素衍生物,采用PEG-400为相转移催化剂进行试验,结果证明PEG-400能明显加快7-羟基-4-甲基香豆素衍生物反应速度,且能大大提高产率。 In order to increase the speed of synthesis of 7-hydroxy-4-methy-coumarin derivatives,phase transfer catalysis of PEG400 was used.It was proved the PEG400 could significantly increase the reaction speed of 7-hydroxy-4-methy-coumarin derivatives and increase the yield greatly.
出处 《广州化工》 CAS 2010年第7期105-106,共2页 GuangZhou Chemical Industry
关键词 相转移催化剂 合成 PEG400 7-羟基-4-甲基香豆素 phase transfer catalysis synthesis PEG400 7-hydroxy-4-methy-coumarin
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  • 2Gormley NA,Orphanides G,Meyer A,et al.The interaction of coumarin antibiotics with fragment of DNA gyrase B protein Biochemistry,1996,35(15):5083.
  • 3Kashman Y,Gustafson K,R,Fuller R W,et al.The calanolides,a novel HIV-inhibitory class of coumarin derivatives from the tyopoical vainforest tree.Calophylum Caniqerunm J Med Chem,1992,35:2735.
  • 4张铭龙,王琳,赵知中.4-甲基香豆素衍生物的合成研究[J].中国药学杂志,1999,34(6):420-422. 被引量:13

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