摘要
目的研究慢性乙肝患者的血清可溶性白细胞介素2受体水平与肝脏炎症及损伤的关系。方法采用ELISA法测定慢乙肝患者及对照组的血清可溶性白细胞介素2受体,并作统计学分析。同时测定慢乙肝患者谷丙转氨酶,透明质酸,并与血清可溶性白细胞介素2受体水平作相关分析。结果慢乙肝患者的血清可溶性白细胞介素2受体水平明显高于正常人并与谷丙转氨酶,透明质酸呈正相关。结论血清白细胞介素2受体参与慢乙肝的病理生理过程,并反映慢乙肝患者的肝脏炎症及损伤程度。
Objective To investigate the relationship between SIL 2R in the patients with chronic hepatitis B and the liver inflammation and damage.Methods The SIL 2R,ALT,HA in the patients with chronic hepatitis B and SIL 2R in the control group were detected.The statistical analysis and correlation analysis were also carried out.Results The level of SIL 2R in the cases was significanty higher than that of the control.SIL 2R and ALT,HA in the cases were positively correlated.Conclusion SIL 2R takes part in the pathophisiology of chronic hepatitis B.SIL 2R is an indicator of the degree of inflammation and damage of the liver by hepatitis B virus.
关键词
乙型肝炎
SIL-2R
谷丙转氨酸
透明质酸
chronic hepatitis B
soluble interleukin 2 receptor
hyaluronic acid
liver inflammation
liver damage