子痫性脑病的CT和MRI特征对比研究

Comparision of Eclamptic Encephalopathy between CT and MRI

目的探讨头部CT和MRI对子痫性脑病的诊断价值。方法收集11例产前子痫性脑病患者、1例产时子痫性脑病患者、3例产后子痫性脑病患者的头颅CT和MRI影像学表现进行回顾性分析。结果 11例患者头颅CT检查发现异常8例,以额、顶、枕叶皮质或皮质下白质内基本对称性斑片状低密度影为主;10例患者头颅MRI均发现异常,病变主要呈T1WI稍低,T2WI稍高信号、FLAIR较高信号,DWI病变呈等及稍高信号,病变主要以双侧额、顶、枕叶及基底核区多见,大多呈可逆性改变;两种检查均发现1例脑出血;初检为CT检查时有3例显示为阴性,阳性者中CT发现病灶数目及部位均较MRI复查时要少。结论 MRI更有助于子痫性脑病的早期诊断和鉴别诊断,对预后及治疗有指导意义。

Objective To incestigate the fetures of cranial CT and MRI in the patients with eclamptic eneephalopathy.Methods The clinical and radiologic datas of 15 patients with eclamptic encephalopathy were analyzed retrospectively,including 11 cases of prenatal eclamptic encephalopathy,one case of intrapartum eclamptic encephalopathy and 3 cases of postpartum eclamptic encephalopathy.Results 8 of eleven cases had abnormal finding in the cranial CT with showed symmetric plaque-like low-attenuated lesions in cortex and subeortieal white matter of frontal,parietal and occipital lobes.10 cases all had abnormal findings in the cranial MRI,the lesions were demonstrated as slightly hypointensity on T1WI and slightly hyperintensity on T2WI and remarkably hyperintensity on FLAIR,and iso or slightly hyperintensity on DWI.The bilateral frontal,parietal and occipital lobes and basal ganglia were the more common sites.CT found the numbers and locations of lesions were less compared with MRI in the same patients.Conclusion MRI can be helpful for early diagnosis and diffenential diagnosis,and conduce to guiding prognosis and treatment of eclamptic encephalopathy.