IOL植入术房水中透明质酸钠与羟丙基甲基纤维素残留量比较

Residue of sodium hyaluronate vs hydroxypropyl methylcellulose in aqueoushumor during IOL implantation

目的比较ＩＯＬ植入术中１％透明质酸钠（ＳＨ）和２％羟丙基甲基纤维素（ＨＰＭＣ）在房水中的残留量。方法将４７例病人随机分为两组，应用ＳＨ组２３例２５眼，ＨＰＭＣ组２４例２６眼。用紫外分光光度仪测量计算ＩＯＬ植入后注吸前及注吸２，５，８（ＳＨ组）或１０ｍｌ（ＨＰＭＣ组）时房水中ＳＨ及ＨＰＭＣ的体积分数。结果ＳＨ组注吸前后不同的体积分数分别是６５．５％，１０．２％，２．１９％及０．７％。ＨＰＭＣ组注吸前后不同的体积分数分别为４７．５６％，３２．７４％，１３．９３％及６．７６％。结论在人工晶状体植入手术中，粘弹剂残留量在注吸清除的各个阶段，ＳＨ组明显比ＨＰＭＣ组低，与清除ＳＨ相比，房水中ＨＰＭＣ较难清除。

ObjectiveTo compare the residue of sodium hyaluronate (SH)1% with hydroxypropyl methylcellulose (HPMC)2% in aqueous humor in IOL implantation.MethodsFourty seven patients (51 eyes) undergoing IOL implantation were randomly divided into two groups.In one group including 23 patients (25 eyes)SH 1% was used as a tool in surgery.In the other group including 24 patients (26 eyes),HPMC 2% was used.The relative percentage concentration of SH and HPMC in aqueous homor was measured and calculated using an ultraviolet spectraphotometer before and after irrigation with balanced salt solution 2 ml,5 ml,and 8 ml in SH group or 10 ml in HPMC group.ResultsThe different relative percentage concentrations of SH before and after irrigation were 65.50%, 10.20% ,2.19% and 0.70% in the SH group.The relative percentage concentrations of HPMC were 47.56%,32.74%,13.93% and 6.76% in HPMC group.ConclusionThe residue of viscoelastic substances was much lower in SH group,compared to the HPMC group in any stages of irrigation.HPMC is more difficult to clear out from aqueous humor than SH.