血管紧张素转换酶2基因G-8790A多态性与原发性高血压合并代谢综合征关系的探讨
被引量：2
摘要
本文以山西籍无血缘关系的汉族人为研究对象,探讨血管紧张素转换酶2（ACE2）基因G-8790A多态性在原发性高血压合并代谢综合征中的作用,对比分析了正常对照组、原发性高血压组及高血压合并代谢综合征（MS）组基因型等位基因的频率差异,
出处
《中国药物与临床》
CAS
2010年第8期895-898,共4页
Chinese Remedies & Clinics
参考文献6
-
1Benjafield AV,Wang WY,Morris BJ.No association of angiotensin-converting enzyme 2 gene(ACE2)polymorphisms with essential hypertension.Am J Hypertens,2004,17:624-628.
-
2Donoghue M,Hsich F,Baronas E,et al.A novel angiotensinconverting enzyme-related carboxy-peptidase(ACE2)conveys angiotensin Ⅰto angiotensin(1-9).Circ Res,2000,87:E1-E9.
-
3Tipnis SR,Hooper NM,Hyde R,el al.A human homolog of angiotensinconverting enzyme cloning and functional expression as a eaptopril-insensitive carboxypeptidnse.J Biol Chem,2000,275(43):33238-33243.
-
4Loudianos G,Lovicu M,Dessi V,et al.Abnormal mRNA splicing resulting from consensus sequence splicing mutations of ATP7B.Hum Mutat,2002,20:260-266.
-
5Huang W,Yang W,Wang Y,et al.Association study of angiotensin-converting enzyme 2 gene(ACE2)polymorphisms and essential hypertension in northern Han Chinese.J Hum Hypertens,2006,20:968-971.
-
6Zhou JB,Yang JK.Meta-analysis of asssociation of ACE2 G8790A polymophism with Chinese Han essential hypertension.Renin Angiotensin Aldosterone Syst,2009,10(1):31-34.
同被引文献15
-
1周亦秋,杨国君.RAS与胰岛素抵抗——代谢综合征新的治疗靶点[J].心血管病学进展,2006,27(6):753-755. 被引量：8
-
2Olivares-Reyes JA, Arellano-Plancarte A, Castillo-Hernandez JR. An- giotensin II and the development of insulin resistance ; implications for diabetes [ J]. Mol Cell Endocrino1,2009,302 ( 2 ) : 128.
-
3朱大年.生理学(第7版):人民卫生出版社,2011,119-121.
-
4Kishi T,Hirooka Y. Sympathoexcitation associated with Renin-Angiotensin system in metabolic syndrome [ J ]. Int J Hypertens,2013,4106897.
-
5Renna NF,Lembo C, Diez E, et al. Role of Renin-Angiotensin system and oxidative stress on vascular inflammation in insulin resistence model[ J]. Int J Hypertens ,2013 ,420979.
-
6Blendea MC, Jacobs D, Stump CS, et al. Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angioten- sin Ⅱ overexpression [ J ]. Am J Physiol Endocrinol Metab,2005,288 (2) :E353-E359.
-
7Lira HS, Mac Fadyen R J, Lip GYH. Diabetes mellitus, the renninan- giotensin-aldosterone system, and the heart [ J ]. Arch Inern Med, 2004,164 (16) : 1737-1748.
-
8H? rdtner C,M? rke C,Wahher R,et al. High glucose activates the altemative ACE2/Ang (1 7 )/Mas and APN/Ang IV/IRAP RAS axes in pancreatic 13 cells [ J ]. Int J Mol Med,2013,32 (4) :795-804.
-
9Saiki A, Ohira M, Endo K, et al. Pisinoglitazone decreases plasma an- giotensin Ⅱ concentration in type 2 diabetes [ J ]. J Atheroscler Thromb,2010,17(6) :651-657.
-
10罗素芬（综述）,晋学庆（审校）.肾素-血管紧张素系统与代谢综合征研究进展[J].医学综述,2009,15(3):464-466. 被引量：9
-
1翁元焦,林莉,许永猛.中老年人脑梗死与代谢综合征关系的临床分析[J].福建医药杂志,2011,33(6):25-26.
-
2陈颖越,金星,蒋兰兰,许向红,马建华,吴锦丹.2型糖尿病高尿酸血症患病特点及与代谢综合征关系的分析研究[J].中国糖尿病杂志,2012,20(12):910-912. 被引量：14
-
3孙志连,李彩萍.脂联素和代谢综合征[J].内蒙古医学杂志,2005,37(11):1048-1051. 被引量：3
-
4郁秀琴,陈双,古丽扎尔.买买提明.抵抗素、CRP、IL-18和白细胞与代谢综合征关系的探讨[J].中华全科医学,2012,10(2):193-194. 被引量：6
-
5眭维国,陈怀周,晏强,车文体,周欣,邹贵勉,谢申平,邹和群.肾移植后胰岛素抵抗的危险因素以及与代谢综合征关系的临床研究[J].中华器官移植杂志,2009,30(5):264-267.
-
6肖玉珍,邵鸣.慢性乙型肝炎合并Dieulafoy1例[J].肝脏,2011,16(4):359-359.
-
7李茜,刘丹,何訸,梁利波,于川,李双庆,安振梅,李舍予.血清Irisin水平与代谢综合征关系的临床研究[J].四川大学学报（医学版）,2017,48(1):136-139. 被引量：2
-
8郭喜朝,张惠军,莫华.冠心病与代谢综合征关系的临床观察[J].中国医药,2007,2(10):587-588. 被引量：5
-
9观晓辉,范碧惠,李韶光.成人非酒精性脂肪性肝病与代谢综合征关系[J].中国公共卫生,2009,25(7):829-830. 被引量：5
-
10赵思文,李万根,吴君洁.颈围与代谢综合征关系及和FEV1相关性[J].热带医学杂志,2016,16(8):1046-1048. 被引量：1
