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Klotho基因功能研究进展 被引量:2

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作者 郜茜
出处 《青海医学院学报》 CAS 2010年第2期123-127,共5页 Journal of Qinghai Medical College
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  • 1Kuro-o M,Matsumura Y,Aizawa H,et al.Mutation of the mouse klotho gene leads to a syndrome resembling ageing[J].Nature,1997,390(6655):45-512.
  • 2Kamemori M,Ohyama Y,Kurabayashi M,et al.Expression of Klotho protein in the inner ear[J].Hear Res,2002,171(1-2):103-110.
  • 3Nagai T,Yamada K,Kim H.C,et al.Cognition impairment in the genetic model of aging klotho gene mutant mice:a role of oxidative stress[J].Faseb J,2003,17(1):50-2.
  • 4Anamizu Y,Kawaguchi H,Seichi A,et al.Klotho insufficiency causes decrease of ribosomal RNA gene transcription activity,cytoplasmic RNA and rough ER in the spinal anterior horn cells[J].Acta Neuropathol,2005,109(5):457-66.
  • 5Arking D E,Becker D M,Yanek L R,et al.KLOTHO allele status and the risk of early-onset occult coronary artery disease[J].Am J Hum Genet,2003,72(5):1154-61.
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  • 7Li S A,Watanabe M,Yamada H,et al.Immunohistochemical localization of Klotho protein in brain,kidney,and reproductive organs of mice[J].Cell Struct Funct,2004,29(4):91-9.
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