85例反流性食管炎临床分析

Clinical analysis of 85 cases of reflux esophagitis

目的探讨反流性食管炎的临床特点及早期诊断和治疗价值。方法 85例反流性食管炎患者按胃镜检查结果分为轻度组和重度组。两组应用西沙比利、奥美拉唑及硫糖铝治疗,治疗8周后行胃镜检查,比较两组的临床疗效。结果轻度组和重度组临床痊愈率分别为51.35%和41.67%,差异无统计学意义(P>0.05);轻度组和重度组临床有效率分别为94.59%和75.00%,差异有统计学意义(P<0.05)。结论早期诊断和治疗反流性食管炎可以提高临床治疗有效率,对降低癌变具有重要临床意义。

Objective To investigate the clinical features of reflux esophagitis,and the value of early diagnosis and treatment.Methods 85 cases of reflux esophagitis were divided into the mild group and severe group by endoscopy.2 groups were treated for 8 weeks by giving cisapride,omeprazole and sucralfatet.To compare the clinical efficacy of 2 groups.Results The cure rate in the mild group was 51.35% and 41.67% in the severe group.There was no significant difference（P0.05）.The clinical effective rate of the mild group was 94.59%,which of the severe group was 75.0%.There was significant difference（P0.05）.Conclusion Early diagnosis and treatment for reflux esophagitis can improve the clinical efficiency.and have important clinical significance of reducing cancerization of reflux esophagitis.