高原成人颈动脉体内电子致密核心囊泡的体视学研究

Stereologic study on electron dense-cord vesicles in carotid bodies in adults on altitudes

目的：研究高原成人颈动脉体（ＣＢ）内电子致密核心囊泡（ＥＤＣＶ）的体视学变化。方法：利用电镜观察１１例高原成人和５例平原成人的ＣＢ超微结构，并用Ｗｅｉｂｅｌ建立的正方测试格点计数法对ＥＤＣＶ进行体视学研究。结果：高原成人ＣＢ内ＥＤＣＶ的体密度（Ｖｖ）、面密度（Ｓｖ）、面数密度（ＮＡ）和数密度（Ｎｖ）均明显高于平原组（Ｐ＜００１），比表面（δ）无明显差异（Ｐ＞００５）。结论：高原成人颈动脉体内ＥＤＣＶ数量增多，大小无明显改变。

AIM:To Study the change of electron dense-cord vesicles (EDCV) on stereology of carotid bodies in adults on altitudes. METHODS:The ultrastructure of carotid bodies was examined by electron microscope in 11 subjects living on altitudes and 5 subjects at sea level. Sterology of EDCV was observed with Weibel's point counting method. RESULTS:Volume density (Vv), surface density (Sv),numberical density on area (N A) and numberical density (Nv) of EDCV on altitudes group were higher than those in control ( P <0.01), but no difference in specific surface (δ) ( P >0.05). CONCLUSION:The number of EDCV in carotid bodies is greater in altitudes adults, but the changes of size are not remarkable.