芪枳黄连汤治疗慢性持续性溃疡性结肠炎临床研究

Clinical Study on Treatment on Chronic Persistent Ulcerative Colitis with Qi-zhi-huang-lian Decotion

目的:研究芪枳黄连汤治疗慢性持续性溃疡性结肠炎的作用机制、临床疗效。方法:将门诊和住院患者随机分为治疗组及对照组,对照组43例口服柳氮磺胺吡啶,治疗组62例在口服柳氮磺胺吡啶的同时加用芪枳黄连汤。结果:治疗组能明显改善临床症状及肠黏膜镜像,其疗效优于对照组(P<0.05)。治疗组的总有效率为88.7%,对照组的总有效率为72.1%,治疗组总有效率明显优于对照组(P<0.05)。结论:芪枳黄连汤可以提高疗效,缩短病程,是治疗慢性持续性溃疡性结肠炎的有效方药。

Objective：To explore the mechanism and clinical effects of treatment on chronic persistent ulcerative colitis with Qi-zhi-huang-lian decotion.Methods：Outpatients and inpatients with chronic persistent ulcerative colitis were randomly divided into treatment group（62 cases） and control group（43 cases）.Sulfasalazine（SASP） were taken by oral in two groups,and Qi-zhi-huang-lian decotion was given additionally in treatment group.Results：The symptoms and intestinal mucosal image in treatment group can be significantly improved,and the curative effect in treatment group is better than that in control group（P〈0.05）.The totally effective rate in treatment group comes to 88.7%,while that in control group is 72.1%.And there is a significant difference between the treatment group and control group（P〈0.05）.Conclusion：Qi-zhi-huang-lian decotion might improve the efficacy and shorten the course of the disease.Qi-zhi-huang-lian decotion is an safe and effective drug of treating chronic persistent ulcerative colitis.