有症状颈动脉狭窄的微栓子信号监测

Microembolic signal monitoring in patients with symptomatic carotid artery stenosis

目的探讨微栓子信号（microembolic signal，MES）与有症状性颈动脉狭窄程度、斑块超声回声、狭窄处收缩期血流速度以及卒中危险因素的关系。方法对52例有症状颈动脉狭窄患者双侧大脑中动脉进行MES监测及颈动脉彩超检查。结果症状侧MES阳性率显著高于无症状侧（28．8％对4．5％，P〈0．05）。MES阳性率与狭窄程度、斑块超声回声、狭窄处收缩期血流速度以及卒中危险因素无显著相关性。结论MES主要发生存症状侧，与斑块不稳定更为密切。

Objective To investigate the relationship of microembolic signals （MESs） between the degree of symptomatic carotid artery stenosis, ultrasonic characteristics of plaques, peak systolic velocity at the stenotic site and risk factors for stroke. Methods A total of 52 patients with symptomatic carotid artery stenosis were enrolled. MESs of bilateral middle cerebral arteries were monitored and detected by carotid color Doppler flow imaging. Results The positive rate of MESs on the symptomatic sides was significantly higher than that on the asymptomatic sides （28.8% vs. 4.5%, P 〈 0.05 ）. The positive rate was not significantly correlated with the degree of stenosis, ultrasonic characteristics of plaques, peak systolic velocity on the stenotic sides, and risk factors for stroke. Conclusions MESs mainly occurred on the symptomatic sides of carotid artery stenosis, and they were more closely correlated with unstable plaques.