依达拉奉和醒脑静治疗急性一氧化碳中毒98例疗效观察

Effect of edaravone with xingnaojing on 98 cases of acute carbon monoxide poisoning

目的:研究依达拉奉和醒脑静合用治疗急性一氧化碳中毒(ACOP)的疗效及其预防迟发性脑病的作用。方法:将196例ACOP患者,分为对照组(常规治疗组)和治疗组(加用依达拉奉和醒脑静注射液),治疗前、后观察两组疗效及迟发性脑病发生率。结果:治疗组临床疗效明显高于对照组,迟发性脑病发生率明显低于对照组,两组间差异有统计学意义(P<0.05)。结论:依达拉奉和醒脑静合用可以明显缩短ACOP患者的意识障碍时间,显著提高疗效,有效减少迟发性脑病的发生率。

Objective： To study the therapeutic effect of edaravone with xingnaojing on acute carbon monoxide poisoning （ACOP） and the preventive effect of delayed encephalopathy. Methods： 196 patients with ACOP were randomly divided into the control group（routine treatment group） and the treatment group（edaravone plus xingnaojing ine treatment group）. Both groups were assessed the clinical curative effect and the incidence of delayed encephalopathy effectively before and after treatment. Results： In the treatment group,the clinical effect and the incidence of delayed encephalopathy effectively were markedly different from those in the control group（P0.05）. Conclusion： Edaravone and xingnaojing can obviously shorten the time of disturbance of consciousness in patients with ACOP,improve efficiency significantly and reduce the in cidence of delayed encephalopathy effectively.