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右美托咪定对二氧化碳潴留并躁动的镇静效果观察 被引量:8

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摘要 目的:探讨右美托咪定应用于ICU二氧化碳潴留并躁动患者镇静的有效性及安全性。方法:将本院2009年10月~2010年5月收入ICU的有二氧化碳潴留(PCO2>60mmHg)并躁动的患者共32例纳入观察组,给予右美托咪定首剂1μg/kg的负荷量于10min推完,给予0.2~0.7μg/(kg·h)的维持量,镇静目标为评分Ramsay2~3分,于用药前、后查血气分析,记录呼气末二氧化碳分压及呼吸频率,对比使用前后上述指标的改变。结果:使用右美托咪定后12hPO2明显下降(P<0.05),SpO2、PO2和呼吸频率于用药后6、12h变化明显(P<0.05),pH值变化不明显。结论:右美托咪定用于二氧化碳潴留患者镇静无呼吸抑制,不加重CO2潴留,无降低氧分压,可保持随时唤醒状态,是ICU二氧化碳潴留并躁动患者安全有效的镇静剂选择。
出处 《中国当代医药》 2010年第21期74-75,共2页 China Modern Medicine
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参考文献6

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共引文献155

同被引文献63

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