中西医结合治疗100例IgA肾病临床病理分析

Analyze the clinical pathology of treating 100 cases of IgA nephropathy in the integrative medicine

目的：探讨中西医结合方法治疗IgA净病的疗效及病理。方法：选择应用中西医结合方法治疗的IgA肾病100例为研究组，同期单独应用西药治疗IgA肾病患者46例为对照组，比较分析治疗组中医证型与临床病理分级的关系，疗程结束后应用Katafuchi积分比较两组治疗效果，3年后随访存活率。结果：中医证型实证患者的病理分级最低，虚证患者病理分级最高，治疗组虚实夹杂证病例疗效显著优于对照组（P〈0．01），3年存活率显著高于对照组。结论：中医辨证与临床病理基本相符，对降低’肾活检对患者的副损伤；中药用量少、作用缓、药效长，可协同作用；中西医结合方法治疗IgA肾病具有单纯西药治疗无法比拟的优势，疗效可靠，值得推广应用。

Objective： To investigate the effect and pathology of treating IgA nephropathy in the integrative medicine. Methods： Ttreating 100 eases of IgA nephropathy in the integrative medicine is study group, treating 46 cases of IgA nephropathy by western medie＇ine is control group, to relatively analyze the relation between clinical syndromes and pathologic grade of treatment groups, to compare the treatment effect of two groups by Kata fuchi integral after treatment, to observe the survival rate afior 3 years. Results： The pathological grade of positive patients is the lowest, the pathological grade of deficiency syndrome patients is the highest, the effect of treatment is better than control group （P〈0.01）, the survival rate of treatment group is higher than control group. Conlusion： Treating in differentiation is same as clinical pathology; the medication of TCM is less, the effect is slow, the efficacy is long; treating IgA nephropathy in the integrative medicine is better than western medicine.