基于离散增量的蛋白质β发夹模体识别

Recognition of β-hairpin motif in the protein based on the algorithm of discrete increments

从蛋白质的氨基酸序列出发,应用离散增量的方法对3088个蛋白质的β发夹模体和非β发夹模体进行了识别.以氨基酸(20种氨基酸和一个空位)和氨基酸紧邻关联为参量,利用10-fold交叉检验的方法进行检验,获得了良好的预测效果.

β-hairpins and non-hairpins motifs of the 3 088 protein chains were recognized by the algorithm of discrete increments.The compositions of amino acids and twin amino acids were chosen as information parameters of the amino acids sequences.10-fold cross-validation methods are used for checking the results of prediction which is proved to be fairly good.