山东省奶牛A型口蹄疫免疫抗体检测与分析

Analysis and detection of serum antibody about bovine FMD type A on Shandong Cattle farms

应用ELISA方法对山东省内应用了口蹄疫A型灭活疫苗34个奶牛饲养户进行了免疫抗体跟踪监测与分析.结果:对18家养牛户进行了免疫抗体检测,各牛场平均抗体合格率为42.4%,其中抗体合格率最高的奶牛场其合格率只有65%,低的只有12.5%,一免后所有18个奶牛场均未达到免疫合格标准;二免后16个奶牛场平均抗体合格率为69.4%,其中,抗体合格率≧70%的有10个牛场,达到免疫合格标准二次免疫后有62.5%(10/16)的达到免疫合格标准.研究表明对于A型口蹄疫疫苗的免疫,首免后必须进行加强免疫.

By ELISA method, antibody tracking for inactivated vaccine of FMD type A is applied on 34 cattle farms in Shandong province. The result indicates： Firstly, immune antibodies are deteced on the 18 cattle farms, and average antibody pass rate of all cattle is 42.4%, in which the highest rate of antibody dairy qualified rate is only 65% and the lowest is only 12.5%, all the 18 dairy farms fail to meet the qualified immunity standard after the first immunization; Secondly, after secondary immune, pass rate of average antibody is 69.4% on 16 cattle farms, and 62.5% （10/16） of the dairy farms achieve the qualified immunity standard after the second immunization. This research demonstrates that the booster immunization should be done after the first immunization for A-type foot and mouth disease.