急性甲胺磷农药中毒早期血药浓度与肿瘤坏死因子-α

The relationship between concentration of methamidophos and level of TNF -αin serum in acute methamidophos poisoned patients

目的探讨急性甲胺磷农药中毒早期血药浓度、TNF-α与中毒程度的关系。方法将92例急性甲胺磷农药中毒患者按中毒程度分为轻中度中毒组、重度中毒组两组,服药后6 h测血清TNF-α及血药浓度,并将两组患者的TNF-α、血药浓度进行统计学分析。结果中毒程度与血药浓度、TNF-α呈正相关。结论 TNF-α、血药浓度在急性甲胺磷农药中毒早期的诊断和病情的估计方面有十分重要的作用。

Objective To study of the relationship between concentration of methamidophos and level of TNF-α in serum in acute methamidophos poisoned patients.Methods 92 patients poisoned by methamidophos were divided into mild-moderate group and severe group according to clinical manifestation.Concentration of methamidophos and level of TNF-α in serum were measured at 6 hours after poisoning.The data were analyzed statistically.Results Concentration of methamidophos and level of TNF-α in serum increased with raised altitude were positive correlated.Conclusion Concentration of methamidophos and level of TNF-α in serum play an important role in the early diagnosis and estimate of acute methamidophos poisoning.