摘要
目的:探讨阿胶复脉汤对内毒素血症时血小板保护作用的机理。方法:复制大鼠内毒素血症动物模型,用血小板聚集仪、透射和扫描电镜等观察阿胶复脉汤对内毒素血症大鼠血液凝固性、血小板聚集性及血小板超微结构变化的影响。结果:阿胶复脉汤可使内毒素血症时明显延长的KPTT和PT时间恢复正常,同时有稳定血小板膜的作用。
OBJECTIVE:To
investigate into the mechanism of Ejiaofumai Decoction in protecting blood platelet in
endotoxemia.METHOD:Rat models with endotoxemia were made and then observations were
made on the effect of this decoction on changes of blood coagulation,blood platelet aggregation
and ultrastructure.RESULT:This decoction can resume the markedly prolonged KPTT and PT
time in endotoxemia and stabilize the membrane of blood platelet.CONCLUSION:Ejiaofumai
Decoction can improve microcirculation and therefore prevent the occurrence of DIC.
出处
《南京中医药大学学报》
CAS
CSCD
1999年第1期25-26,共2页
Journal of Nanjing University of Traditional Chinese Medicine