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强迫症候选基因的研究进展 被引量：3

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摘要 强迫症（OCD）的临床特点是经常性和持久性的思考，和重复性行为或精神行为。研究发现，OCD患者亲属有更大的OCD患病率，而在OCD家庭聚集模式的OCD符合一定遗传模式。双生子的研究发现，同卵双生子患病一致性比非同卵双生子更大并认为，强迫症状遗传度为50％左右。遗传连锁研究发现几个染色体区域与OCD有关。家庭、连锁和关联研究发现一些特定的基因对OCD的发展产生影响。
作者 周朝昀 沙维伟 张晓斌 耿德勤
机构地区 扬州大学医学院附属江苏省扬州五台山医院 徐州医学院附属医院
出处 《中华行为医学与脑科学杂志》 CAS CSCD 北大核心 2010年第7期669-671,共3页 Chinese Journal of Behavioral Medicine and Brain Science
关键词 强迫症状 候选基因 同卵双生子 精神行为 遗传模式 家庭聚集 OCD 临床特点
分类号 R749.7 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献37

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二级参考文献75

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共引文献13

同被引文献21

  • 1王贵山,王冠中,王爱芹,叶萌,张传芝.万拉法新与氯米帕明治疗难治性强迫症的对照研究[J].中国行为医学科学,2004,13(4):405-406. 被引量：11
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引证文献3

二级引证文献12

中华行为医学与脑科学杂志
2010年 第7期

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