米非司酮配伍米索前列醇用于瘢痕子宫中期妊娠引产观察

Observation of Mifepristone and Misoprostol for Mid-pregnancy Abortion with Uterine Scar

目的分析米非司酮配伍米索前列醇用于终止瘢痕子宫中期妊娠的效果。方法回顾分析我科2006年～2009年采用米非司酮口服配伍米索前列醇后穹隆放置用于瘢痕子宫中期妊娠引产资料,并与同期正常子宫中期妊娠引产对比。结果两组引产成功率均为100%,研究组比对照组产后出血量明显增多（P〈0.01）,胎盘残留数明显增高,差异显著（P〈0.05）。两组米索前列醇平均用量、引产时间、不良反应比较差异无统计学意义。结论米非司酮配伍米索前列醇用于瘢痕子宫中期妊娠引产经济、方便、安全有效,值得临床推广应用。

Objective Analysis of Mifepristone and Misoprostol for termination of mid-pregnancy, the effect of uterine scar. Methods Retrospective analysis of our department in 2006～2009 using mifepristone with misoprostol uterine scar after the vault to place for information on mid-pregnancy abortion and compared with normal uterine pregnancy induced labor contrast medium. Results The two groups was 100% successful induction rate of the study group than the control group of postpartum hemorrhage was significantly increased （P0.0l）, significantly increased the number of placental residues, significantly different （P0.05）. Average dosage of misoprostol groups, abortion, adverse events was no significant difference. Conclusions Mifepristone and misoprostol for mid-pregnancy abortion uterine scar economic, convenient, safe and effective, worthy of clinical application.