木村病

Kimura disease

木村病是一种病因未明的累及头颈部浅表淋巴结及软组织的慢性炎症性疾病,属少见病。该病临床主要表现为头颈部无痛性皮下软组织肿块,大涎腺和周围淋巴结常受累,外周血嗜酸性粒细胞和血清IgE增高。组织病理学以淋巴细胞浸润、血管增生及局部嗜酸性粒细胞浸润为特点。对无症状及无损伤外观的病灶可暂时观察。目前治疗手段主要包括手术治疗、药物治疗和放射治疗。

Kimura disease is a chronic inflammatory disorder with unknown etiology. Patients may present with a solitary enlarged painless lymph node or generalized lymphadenopathy. Salivary gland and single or multiple subcutaneous nodules involvement are also frequently observed. Elevated serum eosinophilia and IgE levels are often found in patients with Kimura disease. Incisional biopsy is recommended to obtain the diagnosis. A marked eosinophilic infiltrate and eosinophilic abscesses are present. Observation is acceptable if the lesions are neither symptomatic nor disfiguring. Treatments include surgical care, medication and radiotherapy.