6SMITH M D,TRIANTAFILLOU S,PARKER A,et aL Synovial membrane inflammation and eytokine preduetion in patients with early osteoarthritis [ J ]. J R heumatol, 1997,24 (2) : 365- 371.
7REBOUL P,PELLETIER J P,TARDIF G,et al. The new collagenase-1 collagenase-3 is expressed and synthesized by humen chondrocytes but not synoviocytes:a role in osteoarthritis[J]. J Clin Invest, 1996,97 (8) : 2011-2019.
8FERNIHOU J K,BILLINGHAM M E,CWYFAN HUGES S,et al. Local disruption of the inssulin like growth factor system joint[J]. Arthritis Rheum, 1996,39(9) : 1556-1565.
9EHRLICH M G,ARMSTHRLNG A I,THEADWE B V,et al. Degenerative enzymr systems in cartilage [J]. Clin Orthop, 1985,3(2) : 170-184.
10BLANCO F J, GUITIAN R,VAXQUEZ-MARTUL E,et al. Osteoarthritis chondrocytes die by apoptosis :A possible pathway for osteoarthritis pathology[J]. Arthritis Rheum,1998,41 (2): 284-289.
