缺血性中风与血小板颗粒膜蛋白(GMP—140)关系的临床研究

Lschemic Stroke and GMP-140:A Clinical Study

近年来,在缺血性中风的血液学检测方面,发现了血小板颗粒膜蛋白(GMP—140)在血小板活化、凝集过程中起着重要作用.缺血性中风的主要病机是与动脉粥样硬化和血小板异常凝集形成血栓有关.祖国医学认为缺血性中风是由于各种原因最终导致气滞血瘀而发病.两者在发病机理的认识上有相似之处.本文通过对30例缺血性中风患者及30例健康者的GMP—140含量的测定,发现缺血性中风者的含量明显高于健康者.认为缺血性中风病中血小板CMP—140含量增高可作为该病的客现血液学检测指标之一。

Recently, in hematological examination of ischemic stroke, we find Granular Membrane Protein-140(GMP-140)plays a important role in platelet activating and agglutinating.Now generally acknowledged pathogenesis of ischemic stroke is atherosclerosis and platelet abnormal agglutinating, the consequence is throwbosis.Chinese traditional medicine considers that the stagnation of vital energy and blood stasis is the carse of ischemic stroke.Then we can see,two kinds of medicine have some similarity in pathogensis of ischemic stroke.In this thesis, we observde 30 ischemic stroke patients and 30 healthy people.From examining,we found in the patients' blood serum, the GMP-140 content increased distinctly.So we conclude that GMP-140 can be regard as one of objective hematological examinations of ischemic stroke.