期刊文献+

基于领域本体的生物医学语义检索机制研究——以GoPubMed和SEGoPubMed为例 被引量:3

Research of Biomedical Semantic Retrieval Based On Domain Ontology ——A Case Study of GoPubMed and SEGoPubMed
下载PDF
导出
摘要 基于领域本体对大型文本语料库的语义检索研究成为近年来信息检索领域研究的热点。GoPubMed和SEGoPubMed作为该领域研究成果的杰出代表,为PubMed存在的问题提供了良好的解决方案。对GoPubMed和SEGoPubMed语义检索机制进行深入研究后显示,GoPubMed应用基于语义网的语义分类工具——_GO和MeSH,将PubMed检索结果统计并对应到相应的分类导航目录,使用户利用该导航便可以快速找到自己所需要的文献,但其仍是基于布尔逻辑模型的字符串匹配机制;而比GoPubMed性能更优越的SEGoPubMed应用潜在语义分析(LSA)技术开创了语义敏感地浏览、连接大型文本语料库与本体的新模式,将具有更广泛的应用前景。 Domain ontology based semantic retrieval of the large-scale text corpus has become a hot area of information retrieval research in recent years. GoPubMed and SEGoPubMed, as an outstanding representative of this research area, provide good solutions to the existing problems of PubMed. Our deep studies on semantic search mechanism of GoPubMed and SEGoPubMed have shown that GoPubMed applies Semantic Web-based classification instruments---GO and MESH, measures and corresponds the PubMed search results to the classification of the corresponding navigation directory so that users can use the navigation to quickly find the literature they need, however, it is still based on the string matching mechanism of Boolean logic model. SEGoPubMed,which performaces better than GoPubMed, applies Latent Semantic Analysis (LSA) technology to create a new paradigm to semantic-sensitive ontology based browsing and linking of large corpus to ontologies. The analysis suggests that the SEGoPubmed performs better than the classic GoPubmed as it incorporates semantics. SEGol?ubMed has a brighter future.
作者 杜建 张士靖
出处 《数字图书馆论坛》 2010年第7期56-61,共6页 Digital Library Forum
关键词 领域本体 基因本体 医学主题词表 GOPUBMED SEGoPubMed 潜在语义分析 Domain Ontology, Gene Ontology, MESH, GoPubMed, SEGoPubMed, Latent semantic analysis
  • 相关文献

参考文献12

  • 1PubMed Home[EB/OL].[2009-03-26].http://www.ncbi.nlm.nih.gov/sites/entrez/.
  • 2VANTERU B C,SHAIK J S,YEASIN M.Semantically linking and browsing PubMed abstracts with gene ontology[J].BMC Genomics,2008,9(Suppl 1):S10.
  • 3杨俊柯,杨贯中,杨建学.基于语义模型的信息检索机制研究[J].计算机工程,2006,32(12):212-214. 被引量:2
  • 4Transinsight GmbH-think the impossible[EB/OL].[2009-03-29].http://www.transinsight.com/.
  • 5ASHBURNER M,BALL C,BLAKE J,et al.Gene Ontology:Tool for the unification of biology[J].Nature Genetics,2000,25(1):25-29.
  • 6Gene Ontology Home[EB/OL].[2009-04-06].http://www.geneontology.org/.
  • 7United States.National Library of Medicine.Medical Subject Headings(MESH())[EB/OL].[2009-01-17].http://www.nlm.nih.gov/pubs/factsheets/mesh.html.
  • 8陈龙,朱化彬,沙里金,王栋,王宗礼,程金华,郝海生,杜卫华.蛋白质组学数据库建设的研究进展[J].畜牧与兽医,2008,40(8):102-104. 被引量:4
  • 9DOMS A,SCHROEDER M.GoPubMed:exploring PubMed with the gene ontology[J].Nucleic Acids Res,2005,33,33(Web Server issue):W783-6.
  • 10DOMS A,JAKONIENE V,LAMBRIX P,etc.Ontologies and Text Mining as a Basis for a Semantic Web for the Life Sciences[M].Springer Berlin/Heidelberg,2006.

二级参考文献16

  • 1吴松锋,朱云平,贺福初.人类蛋白质组表达谱蛋白质鉴定的分步搜索策略[J].遗传,2005,27(5):687-693. 被引量:5
  • 2Aebersold R, Goodlett D R. Mass spectrometry in proteomics [ J]. Chemical Reviews, 2001, 101 (2) : 269-292.
  • 3Boeckmann B, Bairoch A, Apweiler R, et al. The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003 [ J ]. Nucleic Acids Research, 2003, 31 (1) : 365-370.
  • 4Apweiler R, Bairoch A, Wu C H. Protein sequence databases [J].Current Opinion in Chemical Biology, 2004, 8: 76-80.
  • 5Wu C H, Nikolskaya A, Huang H Z, et al. PIRSF : Family classification system at the protein information resource [J].Nucleic Acids Research, 2004, 32(1): 112-114.
  • 6Bairoch A, Apweiler R, Wu C H, et al. The universal protein resource (UniProt) [ J ]. Nucleic Acids Research, 2005, 33: 154-159.
  • 7Wu C H, Apweiler R, Bairoch A, et al. The universal protein resource (UniProt): An expanding universe of protein information [J]. Nucleic Acids Research, 2006, 34: 187-191.
  • 8Mann M, Ronald C, Hendriekson, et al. Analysis of proteins and proteomes by mass spectrometry [ J]. Annual Review of Biochemistry, 2001, 70: 450-454.
  • 9Blueggel M, Chamrad D, Meyer H E. Bioinformatics in proteomics [J]. Current Pharmaceutical Biotechnology, 2004, 5: 79-88.
  • 10Rocha C,Schwabe D,Aragao M P.A Hybrid Approach for Searching in the Semantic Web[C].The Thirteenth International World Wide Web Conference,2004-05:17-22.

共引文献4

同被引文献68

引证文献3

二级引证文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部