甲胎蛋白转录调控因子ZHX2与肿瘤

Alpha fetal protein transcriptional regulating factor ZHX2 in tumor

锌指和同源框（ZHX2）是参与甲胎蛋白（AFP）表达调控的一种新型转录抑制因子。研究证明，ZHX2与肝细胞癌（HCC）的发生和转移以及多发性骨髓瘤的侵袭性等有很大关系。

Zinc-fingers and homeoboxes 2 （ZHX2） is a novel transcriptional repression factor participating in regulating the expression of alpha fetal protein （AFP）. ZHX2 has been confirmed to be largely correlated with development and metastasis of hepatocellular carcinoma （HCC） and invasion of multiple myeloma.