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Livin与Fas—FasL在肺癌中的表达及意义

Expression and significance of livin and Fas/FasL in lung cancer
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摘要 凋亡抑制因子Livin和Fas—FasL具有抑制细胞凋亡作用。研究表明Livin在肺癌中过度表达，并促进肿瘤发生发展，Fas-FasL在肺癌中也异常表达。Livin与Fas—FasL的异常表达可能在肺癌变中起协调作用，并有望成为诊断和基因治疗的新靶点。 Livin and Fas-FasL can inhibit cell apotosis. Recent studies show Livin is overexpressed in lung cancer and promotes tumor development. Fas-FasL is expressed abnormally in lung cancer. Aberrant expression of Livin and Fas-FasL may play synergetic roles in lung carcinogenesis, and may be new targets for diagnosis and gene treatment of lung cancer.
作者 苏文媚(综述) 杨志雄(审校)
机构地区 广东医学院附属医院肿瘤中心
出处 《国际肿瘤学杂志》 CAS 2010年第4期293-295,共3页 Journal of International Oncology
关键词 肺肿瘤 细胞凋亡 抑制因子 Lung neoplasms Apoptosis Suppressor factors
分类号 R818.02 [医药卫生—放射医学]
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参考文献13

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国际肿瘤学杂志
2010年 第4期

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