牙周非手术治疗对冠心病患者血脂及C反应蛋白的影响

Effect of non-surgical periodontal therapy on levels of blood lipid and C-reactive protein in patients with coronary heart disease

目的:探讨牙周非手术治疗对伴有中、重度牙周炎的冠心病患者血脂及血清C反应蛋白的影响。方法:选择17名伴有中、重度牙周炎的冠心病患者,比较牙周非手术治疗前及治疗后3个月的出血指数、探诊深度、附着水平、菌斑指数、血脂和血清C反应蛋白水平。结果:牙周非手术治疗后3个月,所有患者的牙周临床指标(探诊深度,附着丧失、出血指数和菌斑指数)均有好转;总胆固醇(TC)、甘油三脂(TG)和低密度脂蛋白(LDL-C)均下降,高密度脂蛋白(HDL-C)明显升高;血清中CRP水平明显降低。结论:牙周非手术治疗有助于降低冠心病患者的血脂和C反应蛋白水平,降低动脉粥样硬化的风险。

Objective： To investigate the effect of non-surgical periodontal therapy on levels of blood lipid and C-reactive protein in patients with coronary heart disease and periodontitis.Methods： 17 coronary heart disease patients with periodontitis were selected.Sulcus bleeding index（BI）,probing index（PD）,attachment level（AL）,plaque index（PLI）,total cholesterol（TC）,triglyceride（TG）,low density lipoproteincholesterol（LDL-C） and high-density lipoprotein cholesterol（HDL-C）and C-reactive protein（CRP） were tested respectively before and 3 months after non-surgical periodontal therapy.Results： 3 months after non-surgical periodontal therapy,all patients demonstrated significant improvement in clinical periodontal status including probing depth（PD）,attachment level（AL）,Sulcus bleeding index and plaque index（PLI）.The level of total cholesterol（TC）,low density lipoprotein cholesterol（LDL-C） and triglyeride cholesterol（TG） decreased.The high density lipoprotein cholesterol（HDL-C） increased.The level of C-reactive protein decreased significantly.Conclusion： The results indicate that non-surgical periodontal therapy can reduce the levels of serum lipid and C-reactive protein,which might be helpful for decreasing risk of coronary heart disease.