不同性别Singh指数与双能X射线骨密度仪测量骨密度的相关性

Relationship between bone mineral density and Singh index of femoral neck in different genders

背景:Singh指数和骨密度测量是临床常用来了解骨强度及骨质疏松情况的方法,而二者之间的相关性及其性别差异性未见报道。目的:了解Singh指数与双能X射线骨密度仪测量骨密度在不同性别的相关性。方法:取股骨颈骨折行假体置换患者股骨颈标本42份,将42份标本按性别分组采用双能X射线骨密度仪测量体外股骨颈骨密度值;对术前X射线片进行Singh指数分级,了解Singh指数与骨密度的双变骨量相关性。结果与结论:男性Singh指数与骨密度的双变骨量相关性分析结果显示,Spearman相关指数r=0.646,P=0.002,二者有非常显著的相关性,并且男性骨密度值与Singh指数有正相关性,根据二者的检查结果可初步判断患者骨质疏松情况;女性Singh指数与骨密度的双变骨量相关性分析结果显示,Spearman相关指数r=0.304,P<0.181,二者无统计学上的相关性,说明女性患者因绝经后骨质疏松加剧,骨密度值与Singh指数相关性不明确,临床治疗时需根据个体情况采用不同治疗方法。

BACKGROUND： Singh index and bone mineral density （BMD） are widely used in measuring bone strength and osteoporosis, however, the relationship between them, as well as difference in genders, are rare reported. OBJECTIVE： To analysis the relationship between BMD and Singh index in different genders. METHODS： A total of 42 samples were collected from patients suffered femoral neck fracture and received operation of total hip replacement. The BMD of primary bearing area was measured by Dual Energy X-Ray Absorptiometry. All the patients had Singh index according to X-ray before operation. The relationship between BMD and Singh index were explored. RESULTS AND CONCLUSION： The correlation index of Spearman in male about Singh index and BMD was r=0.646, P=0.002, which had a significant correlation. In particular, the BMD value was positive associate with Singh index, which could be used in judging the state of osteoporosis. The Spearman index of female about Singh index and BMD was r=0.304, P〈0.181. There was no dramatic correlation between them. It demonstrated that the relationship between Singh index and BMD was unclear for female postmenopausal osteoporosis, thus, clinical treatment should be selected individualized.