玻璃酸钠关节腔注射与运动疗法治疗髋臼发育不良性髋关节骨关节炎

Kinesitherapy in combination with sodium hyaluronate injected into the articular cavity for the treatment of acetabular dysplastic coxarthrosis

背景:人工关节置换对髋臼发育不良性髋关节骨性关节炎早中期患者及年轻患者不是最好的选择,玻璃酸钠具有润滑关节面、滋养和促进关节软骨愈合和再生作用,在软骨早期损害及骨关节炎形成时能有效抑制软骨进一步发生退行性变。目的:探讨玻璃酸钠关节腔注射结合运动疗法治疗髋臼发育不良性髋关节骨关节炎的临床疗效。方法:将38例患者随机分为治疗组20例和对照组18例。治疗组采用玻璃酸钠关节腔注射治疗结合运动疗法,对照组应用综合物理治疗。于治疗前和治疗1个疗程后进行髋关节功能评分(Harris评分)及临床疗效评定。结果与结论:治疗组髋关节Harris评分从治疗前(48.8±8.4)分提高到治疗后的(90.6±5.2)分,临床疗效优良率为90%,对照组髋关节Harris评分从(49.6±9.3)分提高到(76.2±4.8)分,临床疗效优良率为50%,治疗组髋关节Harris评分及临床疗效优良率方面均优于对照组(P<0.05)。结果提示玻璃酸钠关节腔注射结合运动疗法治疗髋臼发育不良性髋关节骨关节炎能明显改善关节功能。

BACKGROUND：Artificial joint replacement is not the best choice for younger patients and patients with early and middle stage of acetabular dysplastic coxarthrosis.Sodium hyaluronate lubricates joints,nourishes and promotes healing and regeneration of the articular cartilage.It can inhibit the degeneration of cartilage when the cartilage early damage and osteoarthritis form.OBJECTIVE：To verify the clinical efficacy of kinesitherapy in combination with sodium hyaluronate injected into the articular cavity in the treatment of acetabular dysplastic coxarthrosis.METHODS：Thirty-eight patients with acetabular dysplastic coxarthrosis were randomly divided into an experimental group（n=20） receiving therapeutic exercise combined with sodium hyaluronate treatment,and a control group（n=18）undergoing comprehensive physical therapy only.The patient＇s hip joint function was evaluated by Harris hip scoring and the clinical efficacy was assessed before and after one course of treatment.RESULTS AND CONCLUSION：The Harris hip scoring of the experimental group ranged from preoperative（48.8±8.4）points to postoperative（90.6±5.2）points.The remarkable effective rate was 90.0%.The Harris hip scoring of the control group ranged from preoperative（49.6±9.3）points to postoperative（76.2±4.8）points.The remarkable effective rate was 50.0%.There was a significant difference in Harris hip scoring and remarkable effective rate between two groups（P〈0.05）.Kinesitherapy in combination with sodium hyaluronate is efficacious in improving joint function of acetabular dysplastic coxarthrosis patients.