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小鼠胎肝激酶-1阳性细胞向胆管细胞和肝细胞分化 被引量：2

FLK-1 in fetal mouse liver identifies a multipotent hepatic precursor which differentiates into cholangiocytes and hepatocytes
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摘要 干细胞对再生医学和人工器官的发展具有巨大潜在应用价值.肝脏可能是再生医学的一个很有吸引力的目标,理由是：（1）肝脏是一种多种遗传性和获得性代谢性疾病的易损器官;（2）增殖肝可接受来自同基因供者的肝细胞.
作者 金成豪 米满吉和 居石克夫 时军
机构地区 江西省人民医院血液内科 Division of Pathophysiological and ExperimentaJ Pathology
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2010年第7期544-545,共2页 Chinese Journal of Hepatology
关键词 干细胞 小鼠 胎肝激酶-1 stem cells Mice Fetal Liver kinase1
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
  • 相关文献

参考文献10

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二级参考文献15

  • 1Libbrecht L, Roskams T. Hepatic progenitor cells in human liver diseases.Semin Cell Dev Biol, 2002, 13: 389-396.
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共引文献2

同被引文献11

  • 1Yamashita J,Itoh H,Hirashima M,et al.Flkl-positive cells derived from embryonic stem cells serve as vascular progenitors.Nature,2000,408:92-96.
  • 2Petersen BE,Bowen WC,Patrene KD,et al.Bone marrow as a potential source of hepatic oval cells.Science,1999,284:1168-1170.
  • 3Lagasse E.Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.Nature Med,2000,6:1229-1234.
  • 4Lin Y,Weisdorf DJ,Solovey A,et al.Origins of circulating endothelial cells and endothelial outgrowth from blood.J Clin Invest,2000,105:71-77.
  • 5Eggermann J,Kliche S,Jarmy G,et al.Endothelial progenitor cell culture and differentiation in vitro:a methodological comparison using human umbilical cord blood.Cardiovasc Res,2003,58:478-486.
  • 6Nichols J,Zevnik B,Anastassiadis K,et al.Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4.Cell,1998,95:379-391.
  • 7Oliva J,French BA,Qing X,et al.The identification of stem cells in human liver diseases and hepatocellular carcinoma.Exp Mol Pathol,2010,88:331-340.
  • 8Mongan NP,Martin KM,Gudas LJ.The putative human stem cell marker,Rex-1 (Zfp42):structural classification and expression in normal human epithelial and carcinoma cell cultures.Mol Carcinog,2006,45:887-900.
  • 9Raman JD,Mongan NP,Liu L,et al.Decreased expression of the human stem cell marker,Rex-1 (zfp-42),in renal cell carcinoma.Carcinogenesis,2006,27:499-507.
  • 10Yu, Y. Yao, A. H. Chen, N. Pu, L. Y. Fan, Y. Lv, L. Sun, B. C. Li, G. Q. Wang, X. H..Mesenchymal stem cells over-expressing hepatocyte growth factor improve small-for-size liver grafts regeneration[J].南京医科大学学报（自然科学版）,2007,27(10):1133-1133. 被引量：46

引证文献2

中华肝脏病杂志
2010年 第7期

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