宫颈癌放疗后致放射性膀胱炎与膀胱癌(附7例报告)

Radiocystitis and bladder carcinoma after radiotherapy of cervical carcinoma (Report of 7 cases)

目的：减少宫颈癌放疗后放射性膀胱炎及膀胱癌的发生。方法：结合文献分析1975～1997年收治的宫颈癌放疗后引起的放射性膀胱炎7例，其中并发膀胱癌5例。并就其临床表现特点及诊断与治疗应注意的问题进行讨论。结果：7例宫颈癌放疗后发生急性放射性膀胱1例，停止放疗后经对症处理痊愈；发生慢性放射性膀胱炎6例，分别经对症处理、膀胱镜下冲洗清除血块、电灼止血痊愈。并发膀胱癌5例，死亡2例，行经尿道膀胱肿瘤切除术3例。结论：放疗对膀胱有损伤及致癌作用，可引起放射性膀胱炎及膀胱瘤。行宫颈癌放疗时应注意保护膀胱，以减少放射性膀胱炎及膀胱癌的发生。

Purpose:To reduce the occurrence of radiocystitis and bladder carcinoma after ra-diotherapy of cervical carcinoma. Metkods: 7 cases of radiocystitis after radiotherapy of cervical car-cinotma from 1975 to 1997 were reported, of which 5 cases complicated with bladder carcinoma'The clinical characteristic and the problems of diagnosis and treatment were discussed. Results:A-cute radiocystitis occurred in one of 7 patients with cervical carcinoma after radiotherapy and curedby expectant treatment after stopping radiotherapy. Chronic radiocystitis occurred in 6 of 7 pa-tients and cured by expectant treatment, cleaning blood clot and electrocautery hemostasis undercystoscope. of 5 cases of bladder carcinoma, 2 died and 3 underwent TURBT. Conclusious:Radio-therapy can result in radiocystitis and bladder carcinoma. It is suggested that the bladder should beprotected during radiotherapy of cervical carcinotna to decrease the occurrence of radiocystitis andbladder carcinotna.