摘要
目的探讨原发性膀胱癌肿瘤浸润淋巴细胞（ＴＩＬ）的体外抗肿瘤作用。方法采用ＬＤＨ释放法。结果该ＴＩＬ对自体肿瘤靶细胞的最高杀伤活性第３０天时为７２．４％，且呈现一定的靶细胞特异性。结论膀胱癌ＴＩＬ在体外经ＩＬ－２培养后对自体肿瘤细胞具有明显的杀伤活性。
Objectives To study the antitumor activity in vitro of Tumor infiltrating lymphocytes (TIL) from a patient with bladder cancer.Methods Using the LDH release assay.Results The TILs showed the highest antitumor activity (72.4%) and target specificity.Conclutions After incubation of TILs in medium with IL-2,the TILs exhibited apparently antitumor activity and specificity to autotumor cells
出处
《宁夏医学杂志》
CAS
1999年第2期65-66,共2页
Ningxia Medical Journal
关键词
肿瘤浸润
白细胞介素-2
膀胱肿瘤
TIL
Tumor-infilerating,lymphocytes
Interleukin-2
Bladder cancer
Cytotoxic activity
